京海黄鸡新城疫和传染性支气管炎抗病性状的全基因组关联分析

doi:10.11843/j.issn.0366-6964.2015.02.004

Abstract

Abstract:

The objective of this study was to seek SNPs that influence Jinghai Yellow chicken’s ND and IB disease resistance character.The SNPs in Jinghai Yellow chicken were detected by SLAF-seq method and then the association of SNP sites with ND and IB disease resistance character were analyzed.The result showed that one SNP was significantly associated with ND disease resistance character，7 SNPs were potential significantly associated with ND disease resistance，and they were located in 5 genes：EEA1，CARS2，SCML2，GRP20 and TOMIL2；All of the 5 genes might influence or regulate organism’s disease resistance and immune ability and could be the candidate genes for Jinghai Yellow chicken’s disease resistance character.No SNP was found that was significantly associated with IB disease resistance character，this trait was complex and was rugulated by many factors.The results showed the 5 genes had influence on Jinghai Yellow chicken’s ND disease resistance characeter，and could provide the reference data for marker assisted selection of Jinghai Yellow chicken’s disease resistant breeding process.

CLC Number:

S831.2

WANG Wen-hao，ZHANG Tao，WANG Jin-yu，ZHANG Gen-xi，FAN Qing-can，CHEN Xue-sen，HAN Kun-peng，WANG Yong-juan. Genome-wide Association Studies for Jinghai Yellow Chicken’s ND and IB Disease Resistance Character[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2015, 46(2): 196-203.

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Genome-wide Association Studies for Jinghai Yellow Chicken’s ND and IB Disease Resistance Character

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